Quasi-experimental study to estimate the effectiveness of seasonal malaria chemoprevention in South Sudan

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Authors: Jamshed Khan, Francis Okot, Abubaker Rom Ayuiel, Jonathan Magoola, Maria Suau Sans, Christian Rassi, Denis Mubiru, Craig Bonnington, Kevin Baker, Sikai Huang, Ahmad Julla, Chuks Nnaji, Sol Richardson

In South Sudan, seasonal malaria chemoprevention reduced malaria in children during the high transmission season, despite potential high levels of resistance.

Seasonal malaria chemoprevention (SMC) is effective in preventing malaria in children, particularly in areas where transmission is seasonal. Due to concerns about sulfadoxine-pyrimethamine (SP) resistance in East and southern Africa (ESA), SMC has primarily been implemented in the Sahel region of West and Central Africa. However, there is growing evidence that suggests SMC with SP and amodiaquine (AQ) retains a high level of effectiveness in ESA. This study assesses the effectiveness of SMC when delivered under programmatic conditions with unknown antimalarial drug resistance in Northern Bahr el Ghazal, South Sudan.

This poster was presented at the 72nd annual meeting of the American Society of Tropical Medicine and Hygiene.

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American Society of Tropical Medicine and Hygiene Annual Meeting

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