The continuing spread of SARS-CoV-2 remains a public health emergency. We postulate that previous infection with the SARS-CoV-2 virus could potentially increase the risk of malaria infection, either through persistent inflammation post SARS-CoV-2 infection or damage to specific tissues targeted by both pathogens, or through ecological, epidemiological, or even sociological factors that increase the probability of exposure to both pathogens. Any possible increase in the risk of contracting malaria would be a major public health concern in sub-Saharan Africa, especially when previous gains in malaria burden reduction over the past decade have recently stalled.
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