Molecular surveillance of sulfadoxine-pyrimethamine and amodiaquine resistance markers in northeastern Uganda
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Resources: Poster
Authors: Richard Kajubi, Anthony Nuwa, Craig Bonnington, Kevin Baker, Musa Odongo, Tonny Kyagulanyi, Victor Asua, Chris Ebong, David Salandini, Jimmy Opigo, Maureen Nakirunda, James Tibenderana
Seasonal malaria chemoprevention has not notably altered sulfadoxine-pyrimethamine resistance after two consecutive annual rounds in northeastern Uganda.
Seasonal malaria chemoprevention (SMC) effectively prevents malaria episodes and deaths in children during the high transmission season. However, adoption of SMC is challenged by parasite resistance to sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) in East and southern Africa. In Uganda’s Karamoja region, we evaluated SPAQ resistance marker changes in children 3–59 months during the 2021 (85,000 children) and 2022 (270,000 children) SMC rounds as part of a protective effectiveness study.
This poster was presented at the 72nd annual meeting of the American Society of Tropical Medicine and Hygiene.
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American Society of Tropical Medicine and Hygiene Annual Meeting