Maximising malaria prevention. Effectiveness of seasonal malaria chemoprevention in Mozambican children: A cluster-randomised controlled trial

Authors: Ivan Alejandro Pulido Tarquino, Kevin Baker, Sol Richardson, Pedro Aide, Chuks Nnaji, Sonia Maria Enosse, Albertino Zunza, Mercia Sitoe, Baltazar Candrinho

Seasonal malaria chemoprevention in Mozambique significantly reduces childhood malaria, with effectiveness increasing through strict treatment adherence.

We assessed the effectiveness of seasonal malaria chemoprevention (SMC) with sulfadoxinepyrimethamine plus amodiaquine (SPAQ) in children 3–59 months during the high transmission season in two districts of Nampula province, Mozambique. By comparing analyses on intention-to-treat (ITT), including children receiving at least one SMC dose, and per-protocol (PP), excluding children who did not receive a full course of SMC, the study aimed to provide a comprehensive understanding of the impact of SMC under different adherence scenarios.

This poster was presented at the Multilateral Initiative on Malaria (MIM) Society's 8th Pan-African Malaria Conference.