Efficacy and safety of intermittent preventive treatment of malaria in school-age children using sulfadoxine-pyrimethamine plus amodiaquine and dihydroartemisinin-piperaquine in rural Burkina Faso

Authors: Jane Achan

Intermittent preventive treatment of malaria in school-age children was found to be safe, effective at preventing malaria and acceptable in this study.

School-age children represent a major reservoir of malaria infection. Intermittent preventive treatment of malaria in school-age children (IPTsc) can help reduce parasitaemia, anaemia and school absenteeism. This cluster-randomised trial of 15 villages in Boussé health district, Burkina Faso revealed dihydroartemisinin-piperaquine plus ivermectin to be the most effective intervention at preventing malaria with a 59 percent risk reduction.

This presentation was given at the 2025 Annual Meeting of the American Society of Tropical Medicine and Hygiene, held on 9-13 November in Toronto, Canada.