Avoiding missed opportunities for perennial malaria chemoprevention: A systematic review of factors influencing the uptake of three other maternal and child health interventions

Authors: Olusola Oresanya, Seyi Soremekun, Michael Ekholuenetale, Roly Gosling, James Tibenderana, Bilal Avan

There is limited evidence on the causes of missed opportunities for perennial malaria chemoprevention (PMC). However, available evidence on the causes of missed opportunities for intermittent preventive treatment in pregnancy, vitamin A supplementation and childhood vaccination can contribute to developing a framework for further research on PMC.

In the face of multiple threats confronting current malaria control tools, there is a growing call to expand the toolbox but also for more effective use and deployment of current interventions. Multipronged approaches tailored to specific epidemiological contexts are more necessary now than ever before. Perennial malaria chemoprevention (PMC), formerly known as intermittent preventive treatment of malaria in infancy with sulfadoxine-pyrimethamine (SP-IPTi), when combined with other interventions, can be an effective tool in this regard. However, missed opportunities for infants to receive PMC during contact with the health system undermine coverage and reduce impact. Previous research has highlighted gaps between vaccination doses and SP doses linked to them; however the evidence for the determinants of missed opportunities for PMC is limited.

This poster was presented at the 2025 Annual Meeting of the American Society of Tropical Medicine and Hygiene, held on 9-13 November in Toronto, Canada.