Thank you for downloading this publication. Please let us know why you chose this publication:
Why are you interested in this publication?
What organisation do you represent?
You will only need to complete this form once per browser/device
How do you prefer to read or receive publications?

We may contact you for feedback on the publication you have downloaded. If you do not want to be contacted, please leave the email field blank. Your information will never be shared with any third party.

Malaria Consortium US Donate
  • About us
    • Who we are
    • Our Strategy
    • Governance
    • Aid transparency
  • Projects
  • Where We Work
  • What we do
    • Diseases
    • Our responses
    • Burden reduction to elimination
    • Data-informed decision-making & digital approaches
    • Health sector resilience
    • Research & policy change
    • Networks & partnerships
  • News & Resources
    • News
    • Blog
    • Videos
    • Webinars
    • Photo stories
  • Publications
    • Interactive publications
  • Support us
  • Contact Us
    • Newsletter
  • Work with us
    • Tenders
  • Home
  • »
  • Publications
  • »
  • Mortality after fluid bolus in African children with severe infection

Share this page

Resources

Latest

Publications

Publication Date:
30/06/2011

Type:
Journal article
Publication

Mortality after fluid bolus in African children with severe infection
Author(s): Kathryn Maitland, Sarah Kiguli, Robert O. Opoka, Charles Engoru, Peter Olupot-Olupot, Samuel O. Akech, Richard Nyeko, George Mtove, Hugh Reyburn, Trudie Lang, Bernadette Brent, Jennifer A. Evans, James K. Tibenderana, Jane Crawley, Elizabeth C. Russell, Michael Levin, Abdel G. Babiker, Diana M. Gibb

Publication Date:
30/06/2011
Type:
Journal article

Abstract

The role of fluid resuscitation in the treatment of children with shock and life threatening infections who live in resource-limited settings is not established. Thus, the study randomly assigned children with severe febrile illness and impaired perfusion to receive boluses of 20 to 40 ml of 5% albumin solution (albumin-bolus group) or 0.9% saline solution (saline-bolus group) per kilogram of body weight or no bolus (control group) at the time of admission to a hospital in Uganda, Kenya, or Tanzania (stratum A), as well as children with severe hypotension were randomly assigned to one of the bolus groups only (stratum B). All children received appropriate antimicrobial treatment, intravenous maintenance fluids, and supportive care, according to guidelines; however children with malnutrition or gastroenteritis were excluded from the data analysis.

Click here to download

Citation: K Maitland et al. for the Feast Trial Group, Mortality after Fluid Bolus in African Children with Severe Infection, N Engl J Med 364;26 nejm.org June 30, 2011

Country: Uganda

Keywords: Case management

 

 

« Back to Publications

Sign up for our newsletter here:

Follow us on our social channels
  • Jobs
  • Contact us
  • Annual reviews
  • Support us
  • About us
  • Sitemap
  • Policies
  • Modern Slavery Statement
Fundraising Regulator logo
© 2023 Malaria Consortium | Charity No. 1099776 | Company No. 4785712